20
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T2963 | Cholic Acid | Cholanic acid,Cholate,Colalin | Endogenous Metabolite |
Cholic Acid (Cholate) is a major primary bile acid produced in the liver and usually conjugated with glycine or taurine. Cholic acid facilitates fat absorption and cholesterol excretion. | |||
T4537 | Cholic acid sodium | SodiumCholate | HIV Protease , Endogenous Metabolite |
Cholic acid sodium (SodiumCholate) exhibits a strong spermicidal and antiviral [anti-human immunodeficiency virus (HIV)-1] activity. | |||
T37854 | Cholic Acid 7-sulfate | ||
Cholic acid 7-sulfate is a metabolite of the primary bile acid cholic acid.[1],[2] It is produced by conjugation of a sulfate group with the hydroxy group at position 7 of cholic acid in the liver and gut. Fecal levels o... | |||
T36075 | Cholic Acid anilide | ||
Cholic acid anilide is a synthetic bile acid and derivative of cholic acid that inhibits the germination of C. difficile strain R20291 spores in vitro (IC50 = 1.8 μM).1 |1. Sharma, S.K., Yip, C., Esposito, E.X., et al. T... | |||
T2744 | Methyl Cholate | Cholic acid methyl ester | Others |
Methyl Cholate (Cholic acid methyl ester) is the methyl form of cholic acid. Cholic acid is a major bile acid produced by the liver and synthesized from cholesterol. | |||
T75427 | Cholic acid sodium hydrate | ||
Cholic acid sodium hydrate, a primary bile acid synthesized in the liver and typically conjugated with glycine or taurine, plays a crucial role in facilitating fat absorption and cholesterol excretion. This compound is o... | |||
TN7120 | 7-keto-deoxycholic acid | 7-Keto-3alpha,12alpha-dihydroxycholanic acid | Others |
7-keto-deoxycholic acid is converted from Lactobacillus and Bifidobacterium with specific condition and from cholic acid in vitro. | |||
T5072 | Glycocholic acid hydrate | Others , Endogenous Metabolite | |
Glycocholic Acid is the product of conjugation of cholic acid with glycine. It is the chief ingredient of the bile of herbivorous animals. | |||
T0408 | Dehydrocholic acid | Dehystolin,Felacrinos,Sanocholen,Decholin | Others |
Dehydrocholic acid (Dehystolin) is a synthetic bile acid, produced by the oxidation of cholic acid. | |||
T1138 | Taurocholic acid sodium salt hydrate | Sodium taurocholate hydrate,Taurocholic Acid sodium hydrate | Others , Potassium Channel , Endogenous Metabolite |
Taurocholic acid sodium salt hydrate (Sodium taurocholate hydrate) is the product of conjugation of taurine with cholic acid. The sodium salt, the main ingredient of the bile of carnivorous animals, is used as a detergen... | |||
T7294 | Aramchol | C20-FABAC | Others |
Aramchol (C20-FABAC), also known as arachidyl amido cholanoic acid, is a conjugate of arachidic acid and cholic acid. It reduces ex vivo cholesterol crystallization in native human bile and dissolves pre-formed cholester... | |||
T19235 | CHAPS | Others | |
CHAPS is a zwitterionic nondenaturing detergent for solubilizing membrane proteins. | |||
T73758 | Glycolithocholic acid 3-sulfate | ||
Glycolithocholic acid 3-sulfate (SLCG), a cholic acid derivative and glycolithocholic acid metabolite, effectively inhibits HIV-1 replication in vitro. This compound holds potential for researching HIV infection and gall... | |||
T83900 | 12β-Hydroxyisocholic Acid | LCA,Lagocholic Acid | |
12β-Hydroxyisocholic acid, a bile acid and an isomer of cholic acid, exhibits increased hepatic levels in a mouse model of alcoholic liver damage. | |||
T37177 | Norcholic Acid | ||
Norcholic acid is a bile acid and 23-carbon derivative of cholic acid .1Levels of norcholic acid are increased in the urine of patients with liver cirrhosis or cerebrotendinous xanthomatosis (CTX), an inborn error of met... | |||
T79424 | TGR5 agonist 3 | ||
Compound 8, a cholic acid derivative, functions as a selective TGR5 agonist and exhibits an EC50 value of 5 μM [1]. | |||
T79425 | TGR5 agonist 4 | ||
TGR5 agonist 4 (compound 19), a derivative of cholic acid, selectively activates the TGR5 receptor with an effective concentration (EC50) of 4 μM [1]. | |||
T35400 | β-Muricholic Acid | β-MCA,5β-Cholanic Acid-3α,6β,7β-triol,β-Muricholic Acid | |
β-Muricholic acid (β-MCA) is a murine-specific primary bile acid.[1],[2] Dietary administration of β-MCA reduces HMG-CoA reductase activity in liver microsomes from mice fed a high cholesterol and cholic acid diet.[3] Di... | |||
T37666 | Trihydroxycholestanoic Acid | Trihydroxycoprostanic Acid | |
Trihydroxycholestanoic acid is an intermediate in the biosynthesis of cholic acid .1 Elevated plasma levels of trihydroxycholestanoic acid have been found in patients with Zellweger syndrome, a neurological disorder char... | |||
T37873 | CAP 3 | ||
CAP 3 is a cholic acid-peptide conjugate (CAP) with antibacterial activity. It is active against the Gram-negative bacteria E. coli, K. pneumoniae, and A. baumanii (MIC99s = 8, 16, and 16 μM, respectively). CAP 3 increas... |